John C Elfar Selected Research

4-Aminopyridine (4 Aminopyridine)

4/2022	Effects of 4-Aminopyridine on Combined Nerve and Muscle Injury and Bone Loss.
1/2021	4-Aminopyridine: A Single-Dose Diagnostic Agent to Differentiate Axonal Continuity in Nerve Injuries.
1/2021	(4-Aminopyridine)-PLGA-PEG as a Novel Thermosensitive and Locally Injectable Treatment for Acute Peripheral Nerve Injury.
11/2020	Human equivalent dose of oral 4-aminopyridine differentiates nerve crush injury from transection injury and improves post-injury function in mice.
1/2020	Transdermal delivery of 4-aminopyridine accelerates motor functional recovery and improves nerve morphology following sciatic nerve crush injury in mice.
1/2019	4-Aminopyridine attenuates muscle atrophy after sciatic nerve crush injury in mice.

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John C Elfar Research Topics

Disease

9	Crush Injuries 04/2022 - 08/2008
9	Peripheral Nerve Injuries 03/2022 - 08/2008
6	Wounds and Injuries (Trauma) 03/2022 - 08/2008
5	Muscular Atrophy (Muscle Atrophy) 04/2022 - 01/2019
3	Multiple Sclerosis 01/2021 - 01/2020
2	Infections 02/2022 - 11/2016
2	Femoral Neck Fractures 11/2016 - 12/2015
2	Pain (Aches) 09/2015 - 12/2014
2	Lacerations 04/2015 - 03/2014
1	Dysbiosis 02/2022
1	Peripheral Nervous System Diseases (PNS Diseases) 02/2022
1	Joint Diseases (Joint Disease) 02/2022
1	Paralysis (Palsy) 01/2021
1	Demyelinating Diseases (Demyelinating Disease) 11/2020
1	Body Weight (Weight, Body) 01/2020
1	Bone Resorption 01/2020
1	Hyperglycemia 01/2020
1	Neoplasms (Cancer) 01/2020
1	Obesity 01/2020
1	Muscle Weakness 01/2020
1	Venous Thrombosis (Deep-Vein Thrombosis) 11/2016
1	Pulmonary Embolism 11/2016
1	Osteoarthritis 11/2015
1	Knee Osteoarthritis 03/2015
1	Fracture Dislocation 02/2015
1	Tennis Elbow (Elbow, Tennis) 12/2014
1	Pressure Ulcer (Bedsore) 09/2014
1	Carpal Tunnel Syndrome 11/2013
1	Arthritis (Polyarthritis) 02/2013
1	Arthrogryposis renal dysfunction cholestasis syndrome 05/2012
1	AIDS-Related Complex (ARC) 05/2012

Drug/Important Bio-Agent (IBA)

6	4-Aminopyridine (4 Aminopyridine)FDA Link 04/2022 - 01/2019
5	Erythropoietin FDA Link 03/2022 - 08/2008
3	Pharmaceutical PreparationsIBA 01/2021 - 01/2020
2	formycin diphosphate (FDP)IBA 04/2015 - 03/2014
1	Saline SolutionIBA 04/2022
1	Fibrin Tissue Adhesive (Fibrin Sealant)IBA 03/2022
1	Butyrates (Butyrate)IBA 02/2022
1	16S Ribosomal RNAIBA 02/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 02/2022
1	Erythropoietin Receptors (Erythropoietin Receptor)IBA 01/2021
1	Hormones (Hormone)IBA 03/2020
1	Neuroprotective AgentsIBA 03/2020
1	Carboplatin (JM8)FDA LinkGeneric 01/2020
1	Zoledronic Acid (Zometa)FDA Link 01/2020
1	Diphosphonates (Bisphosphonates)IBA 01/2020
1	Messenger RNA (mRNA)IBA 01/2020
1	Advanced Glycation End ProductsIBA 01/2020
1	Fibrillar CollagensIBA 01/2020
1	Potassium Channel Blockers (Blockers, Potassium Channel)IBA 01/2019
1	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2014
1	Type A Botulinum Toxins (Botox)FDA Link 12/2014
1	salicylhydroxamic acid (SHAM)IBA 08/2008

Therapy/Procedure

5	Therapeutics 02/2022 - 12/2014
4	Arthroplasty 11/2016 - 02/2013
2	Surgical Amputation (Amputations) 02/2022 - 01/2021
2	Injections 01/2021 - 11/2020
2	Laser Therapy (Surgery, Laser) 01/2020 - 12/2014
2	Hip Replacement Arthroplasty (Total Hip Replacement) 11/2016 - 12/2015
1	Nerve Crush 03/2022
1	Fat-Restricted Diet (Diet, Fat Restricted) 02/2022
1	Electrodes (Electrode) 01/2021
1	Cutaneous Administration 01/2020
1	Aftercare (After-Treatment) 01/2020
1	Drug Therapy (Chemotherapy) 01/2020
1	Hemiarthroplasty 12/2015
1	Osteotomy 11/2015
1	Decompression 09/2015
1	Debridement 03/2015
1	Meniscectomy 03/2015
1	Physical Therapy Modalities (Physical Therapy Technique) 12/2014
1	Extracorporeal Shockwave Therapy 12/2014
1	Prolotherapy 12/2014
1	Length of Stay 09/2014
1	Sutures (Suture) 03/2014
1	Surgical Decompression 11/2013
1	Splints (Splint) 05/2012
1	Denervation 08/2008